All artifacts (778)

Every file produced across the project. 769 are bundled in this archive and downloadable directly; 9 large data/media files are listed with provenance on the external-data page. Download the full index as manifest.csv.

FileTypeSizeSession
πŸ—œeoe_exhaustive_litreview_bundle.tar.gzArchive1.0 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_exhaustive_literature_review.mdText8 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όeoe_evidence_map.pngFigure258 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_review_part4_targeted.mdText10 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_review_part3_pmhc.mdText11 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_review_part2_immune_mechanisms.mdText13 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_review_part1_disease.mdText12 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆeoe_master_reference_library.csvData2.4 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_exhaustive-multi-database-eoe-literature_5eff12f3.jsonData11 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_systematic-literature-review-grounding-t_5eff12f3.jsonData6 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒatopic_march_prevention_review.mdText12 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όatopic_march_prevention.pngFigure270 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒindex_case_groundtruth_calibration.mdText6 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όindex_case_groundtruth_calibration.pngFigure180 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_food_trigger_dx_design.mdText14 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆdx_peptide_pool_spec.csvData512 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όeoe_dx_assay_workflow.pngFigure259 KBDevelop a comprehensive project plan for Phase 1 t
πŸ—œindex_case_deliverables.tar.gzArchive762 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒpersonalized_therapy_plan_index_case.mdText11 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όindex_case_profile.pngFigure254 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_target_assessment.csvData2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_gwas_annotation.csvData2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_allergen_molecule_matrix.csvData462 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_epitope_panel.csvData923 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_personalized-pmhc-effector-target-therap_5eff12f3.jsonData7 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_personalized-pmhc-therapy-plan-for-an-in_5eff12f3.jsonData5 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒvalidation_extension_note.mdText6 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆmhcnuggets_all_alleles.csvData1.2 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpredictor_concordance.csvData290 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_epitope_burden_tiers_13.csvData5 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆallergen_allele_matrix_13.csvData696 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆhla_allele_burden_13.csvData632 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όhla_panel_13allele.pngFigure190 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆeoe_meta_signature_loco_robust.csvData22 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆloco_cohort_summary.csvData348 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆloco_gene_robustness.csvData32 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όloco_robustness.pngFigure165 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_phase4_pmhc_therapy_package.mdText11 KBDevelop a comprehensive project plan for Phase 1 t
πŸ—œphase4_deliverables.tar.gzArchive1.1 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒpreclinical_workflow_roadmap.mdText9 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒt_cell_assay_protocol.mdText29 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒpmhc_tcr_mechanism_review.mdText11 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆepitope_core_matrix.csvData391 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒrecruitment_stratification_rationale.mdText9 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_epitope_burden_tiers.csvData851 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆhla_allele_epitope_analysis.csvData937 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆhla_allele_frequencies.csvData192 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆepitope_cross_reactivity.csvData39 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆepitope_uniqueness.csvData1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆstrong_epitope_binders.csvData206 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆhla_allele_prediction_summary.csvData306 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆallergen_epitope_load.csvData636 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όepitope_load_by_allergen.pngFigure117 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όallergen_epitope_heatmap.pngFigure166 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆallergen_epitope_panel.csvData1.1 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒallergen_sequences.fastaText4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_phase-4-prospective-preclinical-pmhc-tcr_5eff12f3.jsonData8 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒfood_antigen_pmhc_review.mdText6 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpmhc_dual_load.csvData134 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpmhc_ii_candidates.csvData89 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όpmhc_dual_axis.pngFigure102 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_phase3_report.mdText7 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆrevised_design_dossier.csvData873 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όphase3_summary.pngFigure160 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆcompanion_dx_specs.csvData1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όcompanion_dx.pngFigure126 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆantigen_immunogenicity_load.csvData164 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆimmunogenicity_screen.csvData178 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όdevelopability_screen.pngFigure104 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆhlai_delta_bycelltype.csvData523 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆepi_hlai_ifng_persample.csvData673 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpmhc_candidates.csvData46 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆantigen_presentation_scores.csvData777 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όantigen_presentation.pngFigure184 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒbinder_validation_protocol.mdText2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒCCL26_design_brief.mdText2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒIL1RL1_design_brief.mdText1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒSIGLEC6_design_brief.mdText1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ—œdesign_briefs_bundle.tar.gzArchive3 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆbinder_design_targets.csvData606 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆesm_epitope_CCL26.csvData2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆesm_epitope_IL1RL1.csvData8 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆesm_epitope_SIGLEC6.csvData2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆdevelopability_liabilities.csvData650 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όesm_epitope_analysis.pngFigure425 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆdifferentiation_map.csvData1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όdifferentiation_map.pngFigure117 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆiface_CCL26.csvData864 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆiface_SIGLEC6_igv.csvData1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆiface_IL1RL1_bsa.csvData644 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆiface_IL1RL1.csvData591 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆinterface_residues.csvData355 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όinterface_analysis.pngFigure168 KBDevelop a comprehensive project plan for Phase 1 t
🧬4KC3_IL33_ST2.pdbStructure596 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆstructure_inventory.csvData607 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆroster_lock.csvData492 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όroster_structures.pngFigure102 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_phase-3-computational-protein-therapeuti_5eff12f3.jsonData8 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_phase2_report.mdText7 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆrevised_target_dossier.csvData5 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όphase2_summary.pngFigure175 KBDevelop a comprehensive project plan for Phase 1 t
πŸ—œdesign_specs_bundle.tar.gzArchive482 KBDevelop a comprehensive project plan for Phase 1 t
🧬AF-IL1RL1-Q01638.pdbStructure368 KBDevelop a comprehensive project plan for Phase 1 t
🧬AF-SIGLEC6-O43699.pdbStructure292 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒtarget_sequences.fastaText3 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆprotein_design_specs.csvData1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όprotein_design_specs.pngFigure142 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆtarget_biomarker_dossier.csvData4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όtarget_biomarker_dossier.pngFigure144 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆconfirmation_percohort_de.csvData4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆindependent_confirmation.csvData940 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όindependent_confirmation.pngFigure159 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆnovelty_ledger.csvData5 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όnovelty_ledger.pngFigure150 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆgwas_target_overlap.csvData903 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όgwas_overlap.pngFigure95 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆgse303169_ppi_labels.csvData4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆppi_target_triage.csvData2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όppi_response_triage.pngFigure172 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆtarget_addressable_by_endotype.csvData415 BDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆpatient_endotypes_all.csvData13 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όendotype_crosscohort.pngFigure239 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆmastcell_state_markers.csvData105 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όmastcell_states.pngFigure293 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆliana_gerd.csvData1.2 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆliana_healthy.csvData1.0 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆcellcomm_eoe_vs_gerd.csvData10 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όdifferential_cellcomm.pngFigure151 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆifn_module_scores.csvData2 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όifn_deconvolution.pngFigure484 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“Žepithelial_traj.h5ad externalFile1.04 GBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆepithelial_pseudotime.csvData10.8 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆtrajectory_gene_dynamics.csvData3 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όepithelial_trajectory.pngFigure543 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_phase-2-mechanistic-validation-novelty-g_5eff12f3.jsonData10 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆtarget_patient_positivity.csvData1 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆgse250595_endotypes.csvData4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όheterogeneity_preview.pngFigure130 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒSKILL.mdText7 KBDevelop a comprehensive project plan for Phase 1 t
πŸ’»kernel.pyCode4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆmultiomics_support_fullsignature.csvData1.4 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒeoe_phase1_report.mdText10 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆeoe_target_shortlist.csvData5 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όeoe_phase1_summary.pngFigure133 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆtarget_druggability.csvData55 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όtarget_druggability.pngFigure165 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆmirna_de_GSE36727.csvData17 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆmultiomics_evidence.csvData89 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όmultiomics_integration.pngFigure126 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆliana_eoe.csvData1.4 MBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όcellcomm_dotplot.pngFigure230 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆenrich_tf_up.csvData483 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆenrich_down.csvData293 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆenrich_up.csvData568 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όpathway_enrichment.pngFigure142 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“Žgse218607_slim.h5ad externalFile1.08 GBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆsc_celltype_de.csvData21 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆsc_composition.csvData10 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όsc_marker_dotplot.pngFigure65 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όsc_composition.pngFigure84 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όsc_umap_overview.pngFigure1.2 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆeoe_meta_signature_highconf.csvData87 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆeoe_meta_signature.csvData3.8 MBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όmeta_forest_topgenes.pngFigure85 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όmeta_volcano.pngFigure127 KBDevelop a comprehensive project plan for Phase 1 t
πŸ—œde_tables_bundle.tar.gzArchive7.1 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆde_summary.csvData279 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όde_concordance.pngFigure112 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όde_volcanoes.pngFigure499 KBDevelop a comprehensive project plan for Phase 1 t
πŸ—œtier1_harmonized_bundle.tar.gz externalArchive25.2 MBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆcanonical_marker_check.csvData6 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆbulk_qc_metrics.csvData380 BDevelop a comprehensive project plan for Phase 1 t
πŸ–Όcanonical_marker_heatmap.pngFigure140 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όbulk_qc_panels.pngFigure246 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒdataset_prioritization_rationale.mdText4 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όdataset_tiers.pngFigure53 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆdataset_tiers.csvData32 KBDevelop a comprehensive project plan for Phase 1 t
πŸ–Όdataset_landscape.pngFigure104 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆeoe_dataset_inventory.csvData29 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ˆplan_phase-1-exhaustive-mining-of-public-eoe_5eff12f3.jsonData7 KBDevelop a comprehensive project plan for Phase 1 t
πŸ“ƒREADME.mdText3 KBPublish the omics-target-mining skill using the SK
πŸ“ŽLICENSEFile1 KBPublish the omics-target-mining skill using the SK
πŸ“ƒrequirements.txtText267 BPublish the omics-target-mining skill using the SK
πŸ—œomics-target-mining-repo.zipArchive9 KBPublish the omics-target-mining skill using the SK
πŸ“ƒpeer_review_report_round2.mdText71 KBDevelop a comprehensive methods manuscript detaili
πŸ“peer_review_report_round2.docxDocument39 KBDevelop a comprehensive methods manuscript detaili
πŸ“ƒpeer_review_report.mdText64 KBDevelop a comprehensive methods manuscript detaili
πŸ“peer_review_report.docxDocument38 KBDevelop a comprehensive methods manuscript detaili
πŸ“paperE_flagship_manuscript.docxDocument3.4 MBDevelop a comprehensive methods manuscript detaili
πŸ“ƒpaperE_flagship_manuscript.mdText32 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure_preclinical_roadmap.pngFigure254 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure_pmhc_epitope.pngFigure221 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure_companion_dx.pngFigure209 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure1_pipeline_overview.pngFigure222 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆflagship_facts.jsonData5 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆplan_build-integrated-eoe-translational-flags_073a09d1.jsonData5 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆplan_update-paper-d-agentic-workflow-manuscri_073a09d1.jsonData5 KBDevelop a comprehensive methods manuscript detaili
πŸ“paperB_analyses_manuscript.docxDocument2.8 MBDevelop a comprehensive methods manuscript detaili
πŸ“ƒpaperB_analyses_manuscript.mdText24 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆdesign_spec_table.csvData729 BDevelop a comprehensive methods manuscript detaili
πŸ–Όdesign_spec_table.pngFigure160 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure5_designs.pngFigure637 KBDevelop a comprehensive methods manuscript detaili
🧬AF-CCL26-Q9Y258.pdbStructure65 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆtarget_dossier_table.csvData1 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όtarget_dossier_table.pngFigure230 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure4_target_landscape.pngFigure194 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure3_validation.pngFigure328 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure2_singlecell.pngFigure1.1 MBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure1_discovery.pngFigure315 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆpaperB_facts.jsonData3 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆplan_draft-paper-b-eoe-omics-discovery-valida_073a09d1.jsonData6 KBDevelop a comprehensive methods manuscript detaili
πŸ“ƒpaperD_nature_perspective.mdText30 KBDevelop a comprehensive methods manuscript detaili
πŸ“paperD_nature_perspective.docxDocument2.0 MBDevelop a comprehensive methods manuscript detaili
πŸ“ƒpaperD_manuscript_draft.mdText22 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure_panel_paperD.pngFigure3.7 MBDevelop a comprehensive methods manuscript detaili
πŸ“ˆtable3_task_allocation.csvData803 BDevelop a comprehensive methods manuscript detaili
πŸ–Όtable3_task_allocation.pngFigure160 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆtable1_campaign_metrics.csvData1 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όtable1_campaign_metrics.pngFigure214 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure4_lineage_dag.pngFigure625 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure2_operating_model.pngFigure255 KBDevelop a comprehensive methods manuscript detaili
πŸ“ˆcorrection_ledger_T2.csvData2 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure3_correction_ledger.pngFigure567 KBDevelop a comprehensive methods manuscript detaili
πŸ–Όfigure1_campaign_schematic.pngFigure344 KBDevelop a comprehensive methods manuscript detaili
πŸ“ƒpaperD_agentic_workflow_outline.mdText11 KBDevelop a comprehensive methods manuscript detaili
πŸ—œgut_binder_design_bundle.tar.gzArchive399 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_gut_restricted_binder_report.mdText8 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_binder_format_schematic.pngFigure207 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_binder_hardening_fig.pngFigure144 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_binder_protease_map_fig.pngFigure118 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_binder_delivery_spec.jsonData4 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_binder_developability_summary.csvData442 BAdapt and apply our EoE research framework and met
πŸ“ˆceliac_binder_developability.csvData589 BAdapt and apply our EoE research framework and met
πŸ“ƒceliac_binder_hardened.fastaText645 BAdapt and apply our EoE research framework and met
πŸ“ˆceliac_binder_hardened.csvData893 BAdapt and apply our EoE research framework and met
πŸ“ˆceliac_binder_protease_map.csvData12 KBAdapt and apply our EoE research framework and met
πŸ“ˆplan_re-engineer-the-tier-2-protein-binders-i_9f564fe5.jsonData5 KBAdapt and apply our EoE research framework and met
πŸ“ƒgut_restricted_jak_onepager.mdText4 KBAdapt and apply our EoE research framework and met
πŸ–Όgut_restricted_jak_schematic.pngFigure170 KBAdapt and apply our EoE research framework and met
πŸ—œgut_restricted_review_bundle.tar.gzArchive776 KBAdapt and apply our EoE research framework and met
πŸ“ƒgut_restricted_therapeutics_review.mdText11 KBAdapt and apply our EoE research framework and met
πŸ–Όgut_restriction_strategy_taxonomy_fig.pngFigure198 KBAdapt and apply our EoE research framework and met
πŸ–Όgut_restricted_trial_landscape_fig.pngFigure166 KBAdapt and apply our EoE research framework and met
πŸ–Όgut_restricted_evidence_map.pngFigure219 KBAdapt and apply our EoE research framework and met
πŸ“ˆgut_restriction_strategy_taxonomy.csvData4 KBAdapt and apply our EoE research framework and met
πŸ“ˆgut_restricted_approved_drugs.csvData7 KBAdapt and apply our EoE research framework and met
πŸ“ˆgut_restricted_trial_landscape.csvData102 KBAdapt and apply our EoE research framework and met
πŸ“ˆgut_restricted_master_reference_library.csvData908 KBAdapt and apply our EoE research framework and met
πŸ“ˆreview_scope.jsonData3 KBAdapt and apply our EoE research framework and met
πŸ“ˆplan_systematic-landscape-review-of-gut-restr_9f564fe5.jsonData6 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_tier2_design_report.mdText5 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_design_campaign.pngFigure304 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_tier2_best_designs.fastaText631 BAdapt and apply our EoE research framework and met
πŸ“ˆceliac_design_summary.csvData345 BAdapt and apply our EoE research framework and met
πŸ“ˆil15_binder_designs.csvData11 KBAdapt and apply our EoE research framework and met
πŸ“ˆmica_decoy_designs.csvData14 KBAdapt and apply our EoE research framework and met
🧬4GS7.pdbStructure890 KBAdapt and apply our EoE research framework and met
🧬1HYR.pdbStructure394 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_design_spec.jsonData2 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_omics_target_report.mdText12 KBAdapt and apply our EoE research framework and met
πŸ“ˆreport_facts_omics.jsonData608 BAdapt and apply our EoE research framework and met
πŸ“ˆceliac_target_shortlist_tier2.csvData3 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_target_shortlist_tier1.csvData2 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_druggability.pngFigure229 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_target_druggability.csvData15 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_enrichment.pngFigure193 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_enrichment.csvData207 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_sc_validation.pngFigure457 KBAdapt and apply our EoE research framework and met
πŸ“Žceliac_sc_slim.h5ad externalFile28.5 MBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_sc_ifng_test.csvData495 BAdapt and apply our EoE research framework and met
πŸ“ˆceliac_sc_composition.csvData22 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_sc_celltype_expr.csvData107 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_meta_analysis.pngFigure259 KBAdapt and apply our EoE research framework and met
πŸ“ˆde_GSE146190.csvData3.0 MBAdapt and apply our EoE research framework and met
πŸ“ˆde_GSE164883.csvData3.3 MBAdapt and apply our EoE research framework and met
πŸ“ˆde_GSE131705.csvData1.5 MBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_meta_signature.csvData2.5 MBAdapt and apply our EoE research framework and met
πŸ–Όceliac_bulk_qc.pngFigure225 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_bulk_marker_qc.csvData4 KBAdapt and apply our EoE research framework and met
πŸ“Žceliac_bulk_harmonized.pkl externalFile22.3 MBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_dataset_tiers_rationale.mdText2 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_dataset_tiers.csvData9 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_dataset_landscape.pngFigure153 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_dataset_inventory.csvData18 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_tolerability_rubric.mdText4 KBAdapt and apply our EoE research framework and met
πŸ“„fda_celiac_guidance.pdfPDF303 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_patient_preference.csvData2 KBAdapt and apply our EoE research framework and met
πŸ“ˆplan_mine-celiac-mucosal-omics-for-villi-prot_9f564fe5.jsonData7 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_pmhc_stream_report.mdText10 KBAdapt and apply our EoE research framework and met
πŸ“ˆreport_facts.jsonData683 BAdapt and apply our EoE research framework and met
πŸ–Όceliac_epitope_map.pngFigure209 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_epitope_map.csvData4 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_epitope_benchmark.pngFigure278 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_allele_specificity.csvData1 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_epitope_benchmark.csvData2 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_epitope_burden.pngFigure375 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_deamidation_shift.csvData1.5 MBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_epitope_burden.csvData3 KBAdapt and apply our EoE research framework and met
πŸ“ˆiedb_predictions.jsonData8.1 MBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_epitope_panel.csvData5.1 MBAdapt and apply our EoE research framework and met
πŸ–Όceliac_deamidation_map.pngFigure140 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_deamidation_map.csvData23 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_known_epitopes.csvData10 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_gluten_antigens.fastaText8 KBAdapt and apply our EoE research framework and met
πŸ“ˆceliac_gluten_antigen_set.csvData1 KBAdapt and apply our EoE research framework and met
πŸ“ˆplan_celiac-antigen-epitope-pmhc-pipeline-wit_9f564fe5.jsonData6 KBAdapt and apply our EoE research framework and met
πŸ“ƒceliac_transferability_assessment.mdText9 KBAdapt and apply our EoE research framework and met
πŸ–Όceliac_transferability_matrix.pngFigure275 KBAdapt and apply our EoE research framework and met
πŸ“ƒgpu_stalled_tasks_report.mdText7 KBAudit all stalled and postponed tasks requiring GP
πŸ“ˆgpu_stalled_tasks_costs.csvData1 KBAudit all stalled and postponed tasks requiring GP
πŸ–Όgpu_cost_summary.pngFigure153 KBAudit all stalled and postponed tasks requiring GP
πŸ“ƒtranscript_review.mdText11 KBRecord a two-minute podcast discussing progress ma
πŸ’»render.pyCode4 KBRecord a two-minute podcast discussing progress ma
πŸ“ƒrender_brief.mdText2 KBRecord a two-minute podcast discussing progress ma
πŸ“ƒtranscript.mdText10 KBRecord a two-minute podcast discussing progress ma
πŸ“ˆfact_ledger.csvData30 KBRecord a two-minute podcast discussing progress ma
πŸ“ˆscript.jsonData14 KBRecord a two-minute podcast discussing progress ma
πŸ“ƒpodcast_transcript.mdText3 KBRecord a two-minute podcast discussing progress ma
πŸ”Šeoe_hackathon_day2_podcast.wavAudio5.8 MBRecord a two-minute podcast discussing progress ma
πŸ”Šeoe_hackathon_day2_podcast.mp3Audio1.6 MBRecord a two-minute podcast discussing progress ma
πŸ–Όpreview3.pngFigure336 KBDevelop a skill that guides users through preparin
πŸ–Όpreview2.pngFigure353 KBDevelop a skill that guides users through preparin
πŸ–Όpreview1.pngFigure318 KBDevelop a skill that guides users through preparin
πŸ–Όpreview0.pngFigure360 KBDevelop a skill that guides users through preparin
πŸ–Όp2_pipeline.pngFigure110 KBDevelop a skill that guides users through preparin
πŸ–Όp2_trials.pngFigure36 KBDevelop a skill that guides users through preparin
πŸ–Όp3_hlai.pngFigure52 KBDevelop a skill that guides users through preparin
πŸ–Όp3_composition.pngFigure59 KBDevelop a skill that guides users through preparin
πŸ–Όp1_trypsin.pngFigure40 KBDevelop a skill that guides users through preparin
πŸ–Όp1_hardening.pngFigure53 KBDevelop a skill that guides users through preparin
πŸ–Όp0_targets.pngFigure75 KBDevelop a skill that guides users through preparin
πŸ“ƒposter3_eoe_singlecell_speaker_notes.mdText574 BDevelop a skill that guides users through preparin
πŸ“ƒposter2_eoe_pipeline_speaker_notes.mdText640 BDevelop a skill that guides users through preparin
πŸ“ƒposter1_celiac_binder_speaker_notes.mdText615 BDevelop a skill that guides users through preparin
πŸ“ƒposter0_eoe_targets_speaker_notes.mdText644 BDevelop a skill that guides users through preparin
πŸ“ƒposter3_eoe_singlecell_legibility.txtText532 BDevelop a skill that guides users through preparin
πŸ“Šposter3_eoe_singlecell.pptxSlides2.4 MBDevelop a skill that guides users through preparin
πŸ“ƒposter2_eoe_pipeline_legibility.txtText477 BDevelop a skill that guides users through preparin
πŸ“Šposter2_eoe_pipeline.pptxSlides952 KBDevelop a skill that guides users through preparin
πŸ“ƒposter1_celiac_binder_legibility.txtText532 BDevelop a skill that guides users through preparin
πŸ“Šposter1_celiac_binder.pptxSlides669 KBDevelop a skill that guides users through preparin
πŸ“ƒposter0_eoe_targets_legibility.txtText477 BDevelop a skill that guides users through preparin
πŸ“Šposter0_eoe_targets.pptxSlides948 KBDevelop a skill that guides users through preparin
πŸ“ƒpmhc_poster_speaker_notes.mdText1 KBDevelop a skill that guides users through preparin
πŸ“ˆspec_magazine.jsonData7 KBDevelop a skill that guides users through preparin
πŸ–ΌfigD_hardening.pngFigure56 KBDevelop a skill that guides users through preparin
πŸ–ΌfigC_pools.pngFigure55 KBDevelop a skill that guides users through preparin
πŸ–ΌfigB_alleles.pngFigure71 KBDevelop a skill that guides users through preparin
πŸ–ΌfigA_dualload.pngFigure55 KBDevelop a skill that guides users through preparin
πŸ–Όpmhc_poster_preview.pngFigure409 KBDevelop a skill that guides users through preparin
πŸ“ƒpmhc_poster_legibility.txtText477 BDevelop a skill that guides users through preparin
πŸ“Špmhc_poster.pptxSlides246 KBDevelop a skill that guides users through preparin
πŸ–Όposter_preview_justified.pngFigure163 KBDevelop a skill that guides users through preparin
πŸ“ƒskilltest_poster_speaker_notes.mdText397 BDevelop a skill that guides users through preparin
πŸ–Όskilltest_preview.pngFigure162 KBDevelop a skill that guides users through preparin
πŸ“ƒskilltest_poster_legibility.txtText475 BDevelop a skill that guides users through preparin
πŸ“Šskilltest_poster.pptxSlides90 KBDevelop a skill that guides users through preparin
πŸ“EoE_supplementary.docxDocument1.3 MBIdentify and plan strategic uses for $200 in API c
πŸ“EoE_manuscript.docxDocument2.1 MBIdentify and plan strategic uses for $200 in API c
πŸ“„EoE_supplementary.pdfPDF1.6 MBIdentify and plan strategic uses for $200 in API c
πŸ“„EoE_manuscript.pdfPDF2.2 MBIdentify and plan strategic uses for $200 in API c
πŸ“ƒEoE_supplementary.mdText8 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆTableS5_mpnn_summary.csvData10 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆTableS4_foldback_validation.csvData11 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆTableS3_lit_omics_crossref.csvData4 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆTableS2_druggability_shortlist.csvData5 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆTableS1_meta_top60.csvData3 KBIdentify and plan strategic uses for $200 in API c
πŸ“ƒEoE_manuscript.mdText22 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όrender_postn_close.pngFigure553 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όrender_ccl26_close.pngFigure626 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig3_funnel.pngFigure85 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όrender_postn_still.pngFigure420 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όrender_ccl26_still.pngFigure327 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig1_cascade_schematic.pngFigure92 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig5_leads.pngFigure933 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig4_validation.pngFigure210 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig3_pipeline.pngFigure244 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig2_target_selection.pngFigure338 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfig1_graphical_abstract.pngFigure417 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS12_interface_maps.pngFigure101 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS11_ontarget_rank.pngFigure74 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS10_epitope_coverage.pngFigure47 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS9_iptm_plddt.pngFigure145 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS8_complexity_filter.pngFigure217 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS7_mpnn_scores.pngFigure163 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS5_backbone_qc.pngFigure85 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS4_shortlist.pngFigure89 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS3_sc_dotplot.pngFigure85 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS2_concordance.pngFigure128 KBIdentify and plan strategic uses for $200 in API c
πŸ–ΌfigS1_meta_volcano.pngFigure211 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆfigure_plan.jsonData4 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆplan_write-standalone-eoe-de-novo-binder-desi_213e283e.jsonData5 KBIdentify and plan strategic uses for $200 in API c
πŸ“ƒEoE_binder_design_report.mdText7 KBIdentify and plan strategic uses for $200 in API c
🎬POSTN_binder_complex_360.mp4Video1.9 MBIdentify and plan strategic uses for $200 in API c
🎬CCL26_binder_complex_360.mp4Video1.7 MBIdentify and plan strategic uses for $200 in API c
πŸ“ƒlead_spec_sheets.mdText3 KBIdentify and plan strategic uses for $200 in API c
🧬POSTN_lead_complex.pdbStructure140 KBIdentify and plan strategic uses for $200 in API c
🧬CCL26_lead_complex.pdbStructure93 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όfoldback_metrics.pngFigure231 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆeoe_binder_validation.csvData14 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆmpnn_scored.csvData255 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆpostn_qc.csvData893 BIdentify and plan strategic uses for $200 in API c
πŸ“ˆccl26_qc.csvData902 BIdentify and plan strategic uses for $200 in API c
πŸ—œbinder_backbones.tar.gzArchive933 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όtarget_epitopes.pngFigure133 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆtarget_hotspots.jsonData1 KBIdentify and plan strategic uses for $200 in API c
🧬postn_target.pdbStructure182 KBIdentify and plan strategic uses for $200 in API c
🧬ccl26_target.pdbStructure97 KBIdentify and plan strategic uses for $200 in API c
πŸ“ƒeoe_design_rationale.mdText8 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆplan_design-neutralizing-binders-ligand-traps_213e283e.jsonData7 KBIdentify and plan strategic uses for $200 in API c
πŸ“ƒeoe_crossref_report.mdText8 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όeoe_lit_vs_omics_concordance.pngFigure189 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆeoe_crossref_lit_vs_omics.csvData4 KBIdentify and plan strategic uses for $200 in API c
πŸ“ƒeoe_target_report.mdText5 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όeoe_pipeline_summary.pngFigure119 KBIdentify and plan strategic uses for $200 in API c
πŸ–Όeoe_target_landscape.pngFigure151 KBIdentify and plan strategic uses for $200 in API c
πŸ“ˆeoe_target_gap_table.csvData1 KBIdentify and plan strategic uses for $200 in API c
πŸ“ƒWEBSITE_DEPLOYMENT_SUMMARY.mdText8 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒDEPLOYMENT_GUIDE.mdText5 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ—œeoe_program_website_deployment.zipArchive28 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒFINAL_DELIVERABLES_SUMMARY.mdText19 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒEoE_Commercial_Strategy.mdText30 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒEoE_FINAL_INTEGRATED_BUSINESS_SCIENTIFIC_REPORT.mdText31 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“„EoE_FINAL_INTEGRATED_BUSINESS_SCIENTIFIC_REPORT.pdfPDF15 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆplan_generate-integrated-business-plan-and-sc_6cacb9ff.jsonData5 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒDELIVERABLES_FINAL_SUMMARY.txtText10 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒMANUSCRIPT_PACKAGE_SUMMARY.txtText13 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–ΌFigure3_NP_Architecture.pngFigure268 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–ΌFigure1_Epitope_Discovery.pngFigure226 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“EoE_Reviewer_Comments_and_Responses.docxDocument44 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“EoE_Final_Manuscript_Supplemental.docxDocument41 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“EoE_Final_Manuscript_Main.docxDocument680 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒPRESENTATION_GUIDE_WITH_GRAPHICS.txtText24 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ŠEoE_pMHC_Biotech_Pitch_Deck.pptxSlides62 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒVISUALIZATION_ASSETS_CORRECTED.txtText2 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒBIOTECH_PITCH_DECK_GUIDE.txtText22 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ŽEoE_pMHC_Biotech_Pitch_Viewer.htmlFile13 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_preclinical_roadmap_timeline.pngFigure145 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_np_platform_architecture.pngFigure286 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_pmhc_biotech_clip_soy.pngFigure245 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_pmhc_biotech_clip_wheat.pngFigure254 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_pmhc_biotech_clip_dairy.pngFigure243 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒREVISION_SUMMARY.txtText10 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“EoE_pMHC_Therapeutics_Science_Manuscript_Revised.docxDocument43 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒIP_ATTRIBUTION_FRAMEWORK.txtText19 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“EoE_pMHC_Therapeutics_Science_Manuscript.docxDocument43 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒFINAL_SUMMARY.txtText10 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒSCIENCE_MANUSCRIPT_SUBMISSION_INDEX.mdText16 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όfigure3_nanoparticle_architecture.pngFigure363 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όfigure2_structural_validation.pngFigure262 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όfigure1_design_strategy.pngFigure252 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆtable5_risk_assessment.csvData1 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆtable4_preclinical_roadmap.csvData1 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆtable3_nanoparticle_specs.csvData1 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆtable2_structural_metrics.csvData708 BDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆtable1_epitope_selection.csvData700 BDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒScience_manuscript_eoe_pmhc_therapeutics.txtText29 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒaction_plan_12_months.mdText9 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒpeer_review_synthesis.mdText16 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒFINAL_PEER_REVIEW_REPORT.mdText34 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆrisk_feasibility_matrix.csvData7 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆplan_structured-peer-review-with-technical-bi_6cacb9ff.jsonData4 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒDELIVERABLES_INDEX.mdText14 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒeoe_pmhc_hackathon_final_summary.mdText15 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒeoe_pmhc_preclinical_roadmap.mdText29 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒeoe_pmhc_optimization_report.mdText15 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆeoe_pmhc_nanoparticle_assembly_scenarios.csvData465 BDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆeoe_pmhc_nanoparticle_fusion_architecture.csvData1 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_pmhc_nanoparticle_assembly_model.pngFigure248 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆplan_sequence-optimization-and-nanoparticle-s_6cacb9ff.jsonData3 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒeoe_pmhc_therapeutic_report.mdText10 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ—œeoe_pmhc_therapeutic_bundle.tar.gzArchive634 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ–Όeoe_pmhc_strategy_figure.pngFigure418 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆeoe_pmhc_foldback_metrics.csvData248 BDesign peptide-MHC (pMHC) therapeutic candidates t
🧬dairy_singlechain.pdbStructure288 KBDesign peptide-MHC (pMHC) therapeutic candidates t
🧬soy_pmhc.pdbStructure271 KBDesign peptide-MHC (pMHC) therapeutic candidates t
🧬wheat_pmhc.pdbStructure272 KBDesign peptide-MHC (pMHC) therapeutic candidates t
🧬dairy_pmhc.pdbStructure272 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆeoe_pmhc_construct_spec.csvData1 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ƒeoe_pmhc_constructs.fastaText5 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆeoe_pmhc_therapeutic_cores.csvData527 BDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“ˆplan_design-and-visualize-eoe-pmhc-tolerance_6cacb9ff.jsonData4 KBDesign peptide-MHC (pMHC) therapeutic candidates t
πŸ“decoy_control_memo.docxDocument40 KBExecute synthetic peer-review process on EoE de no
πŸ“response_to_reviewers.docxDocument39 KBExecute synthetic peer-review process on EoE de no
πŸ“EoE_supplementary_revised.docxDocument1.6 MBExecute synthetic peer-review process on EoE de no
πŸ“EoE_manuscript_revised.docxDocument2.3 MBExecute synthetic peer-review process on EoE de no
πŸ“ƒresponse_to_reviewers.mdText5 KBExecute synthetic peer-review process on EoE de no
πŸ“ƒEoE_supplementary_revised.mdText11 KBExecute synthetic peer-review process on EoE de no
πŸ“ƒEoE_manuscript_revised.mdText37 KBExecute synthetic peer-review process on EoE de no
πŸ“ˆTableS6_concordance_and_controls.csvData8 KBExecute synthetic peer-review process on EoE de no
πŸ“ˆchai_boltz_concordance.csvData16 KBExecute synthetic peer-review process on EoE de no
πŸ–Όchai_concordance.pngFigure96 KBExecute synthetic peer-review process on EoE de no
πŸ“ƒdecoy_control_memo.mdText7 KBExecute synthetic peer-review process on EoE de no
πŸ“ˆdecoy_control_spec.csvData5 KBExecute synthetic peer-review process on EoE de no
πŸ“ˆdecoy_control_results.csvData8 KBExecute synthetic peer-review process on EoE de no
πŸ–Όdecoy_calibration.pngFigure111 KBExecute synthetic peer-review process on EoE de no
πŸ“ƒrevision_plan.mdText11 KBExecute synthetic peer-review process on EoE de no
πŸ“ƒpeer_review_report.mdText59 KBExecute synthetic peer-review process on EoE de no
πŸ“peer_review_report.docxDocument36 KBExecute synthetic peer-review process on EoE de no
πŸ“EoE_hackathon_notice_AI_Research_Lead.docxDocument38 KBDraft and send a professional heads-up message to
πŸ“EoE_hackathon_notice_Legal.docxDocument38 KBDraft and send a professional heads-up message to
πŸ“ƒmarket_access_strategy.mdText6 KBEstablish biotech company name, brand identity, an
πŸ–Όmarket_access.pngFigure269 KBEstablish biotech company name, brand identity, an
πŸ“ƒREADME_fundraising_bundle.mdText3 KBEstablish biotech company name, brand identity, an
πŸ“ƒexecutive_onepager.mdText3 KBEstablish biotech company name, brand identity, an
πŸ—œcompany_launch_bundle.tar.gzArchive5.4 MBEstablish biotech company name, brand identity, an
πŸ“ŽTolera_Bio_VC_Pitch_Viewer.htmlFile2.6 MBEstablish biotech company name, brand identity, an
πŸ“ŠTolera_Bio_VC_Pitch_Deck.pptxSlides2.1 MBEstablish biotech company name, brand identity, an
πŸ“ƒfinancial_model.mdText4 KBEstablish biotech company name, brand identity, an
πŸ–Όmilestone_timeline.pngFigure144 KBEstablish biotech company name, brand identity, an
πŸ–Όuse_of_proceeds.pngFigure131 KBEstablish biotech company name, brand identity, an
πŸ“ˆmilestones.csvData641 BEstablish biotech company name, brand identity, an
πŸ“ˆfinancial_model.csvData758 BEstablish biotech company name, brand identity, an
πŸ“ƒmarket_analysis.mdText5 KBEstablish biotech company name, brand identity, an
πŸ–Όmarket_analysis.pngFigure189 KBEstablish biotech company name, brand identity, an
πŸ“ˆcost_of_care_10yr.csvData236 BEstablish biotech company name, brand identity, an
πŸ“ˆmarket_model.csvData195 BEstablish biotech company name, brand identity, an
πŸ“ƒregulatory_strategy.mdText11 KBEstablish biotech company name, brand identity, an
πŸ–Όregulatory_timeline.pngFigure121 KBEstablish biotech company name, brand identity, an
πŸ–Όpopulation_coverage.pngFigure201 KBEstablish biotech company name, brand identity, an
πŸ“ˆcoverage_analysis.csvData2 KBEstablish biotech company name, brand identity, an
πŸ“ƒplatform_spec.mdText5 KBEstablish biotech company name, brand identity, an
πŸ–Όpersonalization_decision_tree.pngFigure174 KBEstablish biotech company name, brand identity, an
πŸ–Όplatform_architecture.pngFigure193 KBEstablish biotech company name, brand identity, an
πŸ“ƒcompany_brand_brief.mdText6 KBEstablish biotech company name, brand identity, an
πŸ–Όbrand_hero.pngFigure130 KBEstablish biotech company name, brand identity, an
πŸ“ˆplan_build-the-company-platform-and-regulator_ccdd12cf.jsonData7 KBEstablish biotech company name, brand identity, an
🧬soy_singlechain.pdbStructure287 KBAdd wheat PDB file references to Blender and Chime
🧬wheat_singlechain.pdbStructure288 KBAdd wheat PDB file references to Blender and Chime
🧬dairy_tetramer.pdbStructure1.4 MBAdd wheat PDB file references to Blender and Chime
🧬streptavidin_core.pdbStructure310 KBAdd wheat PDB file references to Blender and Chime
πŸ“Žpmhc_delivery_formats.cxcFile6 KBAdd wheat PDB file references to Blender and Chime
πŸ’»tcell_threefate_scene_v3_cycles.pyCode33 KBAdd wheat PDB file references to Blender and Chime
πŸ“ƒmodal_blender_render_recipe.mdText4 KBResolve IndentationError in Blender console script
πŸ’»render_range.pyCode2 KBResolve IndentationError in Blender console script
πŸ–Όstill_420_end.pngFigure1.8 MBResolve IndentationError in Blender console script
πŸ–Όstill_300_resolving.pngFigure1.8 MBResolve IndentationError in Blender console script
πŸ–Όstill_120_docked.pngFigure1.7 MBResolve IndentationError in Blender console script
πŸ–Όstill_001_start.pngFigure1.7 MBResolve IndentationError in Blender console script
🎬tcell_threefate_animation.mp4Video3.2 MBResolve IndentationError in Blender console script
πŸ–Όqc_frame_0360_labelfix.pngFigure2.1 MBResolve IndentationError in Blender console script
πŸ“Žtcell_threefate_scene_labelfix.blendFile1.1 MBResolve IndentationError in Blender console script
πŸ“Žtcell_threefate_scene.blendFile1.1 MBResolve IndentationError in Blender console script
πŸ“ˆplan_render-the-t-cell-three-fate-animation-o_a7a47f15.jsonData5 KBResolve IndentationError in Blender console script
πŸ’»mn_style_helper.pyCode24 KBResolve IndentationError in Blender console script
πŸ–Όeosinophil_cartoon.pngFigure80 KBConduct a comprehensive 100+ page market report on
πŸ“ƒeoe_survey_plan.mdText17 KBConduct a comprehensive 100+ page market report on
πŸ“ƒappendix_trials.mdText12 KBConduct a comprehensive 100+ page market report on
πŸ“ƒglossary.mdText7 KBConduct a comprehensive 100+ page market report on
πŸ“ƒeoe_journey.mdText5 KBConduct a comprehensive 100+ page market report on
πŸ“ƒeoe_pipeline.mdText7 KBConduct a comprehensive 100+ page market report on
πŸ“ƒregulatory.mdText9 KBConduct a comprehensive 100+ page market report on
πŸ“ƒmarket_context.mdText6 KBConduct a comprehensive 100+ page market report on
πŸ“Žpmhc_landscape_report.htmlFile1.1 MBConduct a comprehensive 100+ page market report on
πŸ“„pmhc_landscape_report.pdfPDF1.6 MBConduct a comprehensive 100+ page market report on
πŸ“ƒsynthesis_eoe.mdText6 KBConduct a comprehensive 100+ page market report on
πŸ–Όfig_landscape_matrix.pngFigure104 KBConduct a comprehensive 100+ page market report on
πŸ“ƒpfdd_timeline.mdText5 KBConduct a comprehensive 100+ page market report on
πŸ“ˆpfdd_inventory.csvData2 KBConduct a comprehensive 100+ page market report on
πŸ–Όfig_pfdd_timing.pngFigure95 KBConduct a comprehensive 100+ page market report on
πŸ“ƒpatient_voice.mdText7 KBConduct a comprehensive 100+ page market report on
πŸ“ˆpro_instruments.csvData2 KBConduct a comprehensive 100+ page market report on
πŸ“ƒtzield_postmarket.mdText6 KBConduct a comprehensive 100+ page market report on
πŸ–Όfig_tzield_timeline.pngFigure107 KBConduct a comprehensive 100+ page market report on
πŸ“ƒoutcomes_analysis.mdText9 KBConduct a comprehensive 100+ page market report on
πŸ“ˆoutcomes_matrix.csvData2 KBConduct a comprehensive 100+ page market report on
πŸ–Όfig_outcomes_matrix.pngFigure159 KBConduct a comprehensive 100+ page market report on
πŸ“ƒorigins_preclinical.mdText13 KBConduct a comprehensive 100+ page market report on
πŸ“ˆcitation_library_final.jsonData4 KBConduct a comprehensive 100+ page market report on
πŸ“ˆtrials_master.csvData47 KBConduct a comprehensive 100+ page market report on
πŸ–Όfig_trial_timeline.pngFigure76 KBConduct a comprehensive 100+ page market report on
πŸ“ƒreport_outline.mdText8 KBConduct a comprehensive 100+ page market report on
πŸ“ˆprogram_roster.csvData3 KBConduct a comprehensive 100+ page market report on
πŸ“ˆplan_patient-centered-pmhc-antigen-specific-i_3840a12c.jsonData8 KBConduct a comprehensive 100+ page market report on
πŸ“ƒEoE_linkedin_post.mdText4 KBCreate a 5-minute survey on EoE patient experience
πŸ“ƒEoE_survey_distribution.mdText2 KBCreate a 5-minute survey on EoE patient experience
πŸ’»build_EoE_form.gsCode6 KBCreate a 5-minute survey on EoE patient experience
πŸ“ƒEoE_tolerizing_vaccine_survey.mdText4 KBCreate a 5-minute survey on EoE patient experience
πŸ—œpatient-centered-market-and-survey-skill.tar.gzArchive32 KBDevelop and publish a reusable skill to GitHub for
πŸ“ŠProject_Tolera_Roadmap.pptxSlides2.5 MBIntegrate insights from the patient-centered marke
πŸ“ƒteaser_onepager.mdText4 KBIntegrate insights from the patient-centered marke
πŸ“„teaser_onepager.pdfPDF42 KBIntegrate insights from the patient-centered marke
πŸ“ŠTolera_Bio_VC_Pitch_Deck_v2.pptxSlides2.5 MBIntegrate insights from the patient-centered marke
πŸ“„scientific_plan.pdfPDF461 KBIntegrate insights from the patient-centered marke
πŸ“„business_plan.pdfPDF2.4 MBIntegrate insights from the patient-centered marke
πŸ“ƒscientific_plan.mdText18 KBIntegrate insights from the patient-centered marke
πŸ“ƒbusiness_plan.mdText27 KBIntegrate insights from the patient-centered marke
πŸ–Όfig_market_v2.pngFigure196 KBIntegrate insights from the patient-centered marke
πŸ–Όfig_scientific_roadmap.pngFigure378 KBIntegrate insights from the patient-centered marke
πŸ–Όfig_payer_value.pngFigure347 KBIntegrate insights from the patient-centered marke
πŸ–Όfig_whitespace.pngFigure199 KBIntegrate insights from the patient-centered marke
πŸ–Όfig_patient_priorities.pngFigure346 KBIntegrate insights from the patient-centered marke
πŸ“ˆnumber_reconciliation.csvData975 BIntegrate insights from the patient-centered marke
πŸ“ˆplan_fresh-pitch-deck-business-plan-and-ai-to_2710584a.jsonData6 KBIntegrate insights from the patient-centered marke
πŸ“ˆmanuscript_references.csvData3 KBUpdate the "Rational design of multivalent nanopar
πŸ“EoE_manuscript_personalized_supplemental.docxDocument42 KBUpdate the "Rational design of multivalent nanopar
πŸ“ƒmanuscript_changelog.mdText9 KBUpdate the "Rational design of multivalent nanopar
πŸ“ƒEoE_manuscript_personalized.mdText28 KBUpdate the "Rational design of multivalent nanopar
πŸ“EoE_manuscript_personalized.docxDocument827 KBUpdate the "Rational design of multivalent nanopar
πŸ“ˆpmhc_ii_candidates_msw.csvData390 KBUpdate the "Rational design of multivalent nanopar
πŸ–Όfig_personalization_engine.pngFigure254 KBUpdate the "Rational design of multivalent nanopar
πŸ“ˆmanuscript_reconciliation.csvData5 KBUpdate the "Rational design of multivalent nanopar
πŸ“ˆplan_reposition-the-eoe-pmhc-ii-manuscript-ar_cc781c80.jsonData5 KBUpdate the "Rational design of multivalent nanopar
πŸ–Όgfx_vaccine.pngFigure118 KBCreate a bare bones slide deck walking through the
πŸ–Όgfx_burden.pngFigure236 KBCreate a bare bones slide deck walking through the
πŸ–Όdk2_eosinophil.pngFigure67 KBCreate a bare bones slide deck walking through the
πŸ–Όdk2_hero.pngFigure117 KBCreate a bare bones slide deck walking through the
πŸ–Όdk2_funnel.pngFigure123 KBCreate a bare bones slide deck walking through the
πŸ–Όdk2_roadmap.pngFigure242 KBCreate a bare bones slide deck walking through the
πŸ–Όdk2_landscape.pngFigure170 KBCreate a bare bones slide deck walking through the
πŸ–Όdk2_volcano.pngFigure195 KBCreate a bare bones slide deck walking through the
πŸ–Όgfx_specialist.pngFigure135 KBCreate a bare bones slide deck walking through the
πŸ–Όindex.pngFigure871 KBCreate a bare bones slide deck walking through the
🎬site_walkthrough.mp4 externalVideo43.1 MBCreate a bare bones slide deck walking through the
πŸ–Όgfx_scale.pngFigure199 KBCreate a bare bones slide deck walking through the
πŸ–Όgfx_design.pngFigure137 KBCreate a bare bones slide deck walking through the
πŸ–Όgfx_triad.pngFigure137 KBCreate a bare bones slide deck walking through the
πŸ“ŠTolera_hackathon_video_deck.pptx externalSlides50.3 MBCreate a bare bones slide deck walking through the
πŸ“ƒdryrun_SMA_genetic.mdText3 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒgenetic_modality_tree.mdText3 KBBuild a generalizable Claude Science tool that aut
πŸ“ˆgenetic_modality_tree.csvData3 KBBuild a generalizable Claude Science tool that aut
πŸ“ˆplan_make-the-drug-program-pipeline-archetype_440da737.jsonData5 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒorchestration_readme.mdText5 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒdryrun_IPF.mdText3 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒSKILL.mdText14 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒprogram_summary_template.mdText1 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒscientific_plan_template.mdText3 KBBuild a generalizable Claude Science tool that aut
πŸ“ˆtarget_modality_rubric.csvData1 KBBuild a generalizable Claude Science tool that aut
πŸ’»kernel.pyCode31 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒcheckpoint_protocol.mdText9 KBBuild a generalizable Claude Science tool that aut
πŸ“ˆprogram_dossier.schema.jsonData6 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒstage_spec.mdText24 KBBuild a generalizable Claude Science tool that aut
πŸ“ˆcheckpoint_map.csvData4 KBBuild a generalizable Claude Science tool that aut
πŸ“ˆplan_build-a-disease-agnostic-drug-program-or_440da737.jsonData5 KBBuild a generalizable Claude Science tool that aut
πŸ“ƒmarket_analysis.mdText5 KBCreate a central website that showcases hackathon
πŸ“ƒREADME.mdText2 KBCreate a central website that showcases hackathon
πŸ“Žabout.htmlFile9 KBCreate a central website that showcases hackathon
πŸ“Žbiotech.htmlFile22 KBCreate a central website that showcases hackathon
πŸ“Žmanuscripts.htmlFile14 KBCreate a central website that showcases hackathon
πŸ“Žspecialist.htmlFile12 KBCreate a central website that showcases hackathon
πŸ“Žsoftware.htmlFile14 KBCreate a central website that showcases hackathon
πŸ“Žindex.htmlFile11 KBCreate a central website that showcases hackathon
πŸ—œruthannepai-site.zipArchive7.8 MBCreate a central website that showcases hackathon
πŸ“ˆasset_manifest.csvData5 KBCreate a central website that showcases hackathon
πŸ’»pages.pyCode77 KBCreate a central website that showcases hackathon
πŸ’»build.pyCode5 KBCreate a central website that showcases hackathon
πŸ“Žstyle.cssFile18 KBCreate a central website that showcases hackathon
πŸ“ˆplan_build-a-static-multi-page-website-showca_545c5625.jsonData6 KBCreate a central website that showcases hackathon
πŸ“ƒFINAL_program_deliverable.mdText5 KBExecute the drug program pipeline for esophageal c
πŸ“ƒcommercial_financing_brief.mdText4 KBExecute the drug program pipeline for esophageal c
πŸ“ƒregulatory_brief.mdText4 KBExecute the drug program pipeline for esophageal c
πŸ“ƒscientific_development_plan.mdText9 KBExecute the drug program pipeline for esophageal c
🧬dkk1_bb1_complex.pdbStructure91 KBExecute the drug program pipeline for esophageal c
🧬gucy2c_bb2_complex.pdbStructure301 KBExecute the drug program pipeline for esophageal c
πŸ“ˆdesign_leads.csvData2 KBExecute the drug program pipeline for esophageal c
πŸ–Όdesign_results.pngFigure180 KBExecute the drug program pipeline for esophageal c
πŸ“ˆtarget_nomination.csvData4 KBExecute the drug program pipeline for esophageal c
πŸ–Όtarget_nomination.pngFigure155 KBExecute the drug program pipeline for esophageal c
πŸ“ˆcompetitive_landscape.csvData2 KBExecute the drug program pipeline for esophageal c
πŸ–Όeac_whitespace_map.pngFigure174 KBExecute the drug program pipeline for esophageal c
πŸ“ƒpatient_priorities_brief.mdText4 KBExecute the drug program pipeline for esophageal c
πŸ“ˆprogram_dossier.jsonData21 KBExecute the drug program pipeline for esophageal c
πŸ–Όeac_driver_landscape.pngFigure96 KBExecute the drug program pipeline for esophageal c
πŸ“ˆplan_end-to-end-drug-program-for-esophageal-a_d913017f.jsonData6 KBExecute the drug program pipeline for esophageal c
πŸ“peer_review_report.docxDocument68 KBExecute the manuscript specialist tool on the EAC
πŸ“manuscript_and_supplements.docxDocument761 KBExecute the manuscript specialist tool on the EAC
πŸ“lay_abstract.docxDocument12 KBExecute the manuscript specialist tool on the EAC
πŸ“executive_summary.docxDocument13 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒREADME.mdText3 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒpeer_review_report_combined.mdText142 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒlay_abstract.mdText2 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒexecutive_summary.mdText4 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒresponse_to_reviewers_round2.mdText4 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒfigure_legends_v3.mdText4 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒmanuscript_v3.mdText30 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒpeer_review_round2.mdText69 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒresponse_to_reviewers_round1.mdText6 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒsupplementary_information_v2.mdText22 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒmanuscript_v2.mdText28 KBExecute the manuscript specialist tool on the EAC
πŸ“ˆS5_binder_liabilities.csvData821 BExecute the manuscript specialist tool on the EAC
πŸ“ˆS4_gtex_selectivity.csvData642 BExecute the manuscript specialist tool on the EAC
πŸ–ΌfigureS1_gtex.pngFigure154 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒpeer_review_round1.mdText58 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒfigure_legends.mdText3 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒsupplementary_information.mdText13 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒmanuscript.mdText21 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒmanuscript_v1.mdText57 KBExecute the manuscript specialist tool on the EAC
πŸ“ˆS3_competitive_landscape.csvData2 KBExecute the manuscript specialist tool on the EAC
πŸ“ˆS2_target_nomination.csvData2 KBExecute the manuscript specialist tool on the EAC
πŸ“ˆS1_binder_designs.csvData2 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒreferences.mdText2 KBExecute the manuscript specialist tool on the EAC
πŸ“ˆclaims_to_sources.csvData2 KBExecute the manuscript specialist tool on the EAC
πŸ–Όfigure4.pngFigure195 KBExecute the manuscript specialist tool on the EAC
πŸ–Όfigure3.pngFigure180 KBExecute the manuscript specialist tool on the EAC
πŸ–Όfigure2.pngFigure108 KBExecute the manuscript specialist tool on the EAC
πŸ–Όfigure1.pngFigure174 KBExecute the manuscript specialist tool on the EAC
πŸ“ƒmanuscript_outline.mdText4 KBExecute the manuscript specialist tool on the EAC
πŸ“ˆplan_turn-the-eac-dual-arm-drug-program-into_3d43be4f.jsonData6 KBExecute the manuscript specialist tool on the EAC
πŸ—œeoe-protein-design-skills.tar.gzArchive25 KBReview completed work across therapeutics, softwar
πŸ“ƒreconstruction_notes.mdText7 KBReview completed work across therapeutics, softwar
πŸ“ˆplan_author-5-skills-1-specialist-from-the-eo_f387d4c7.jsonData6 KBReview completed work across therapeutics, softwar
πŸ“ƒexec_summary_pMHC_nanoparticle.mdText3 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“ƒexec_summary_pMHC_personalized.mdText4 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“ƒexec_summary_CCL26_POSTN.mdText4 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“exec_summary_pMHC_nanoparticle.docxDocument38 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“exec_summary_pMHC_personalized.docxDocument39 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“exec_summary_CCL26_POSTN.docxDocument39 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“lay_summary_pMHC_nanoparticle.docxDocument38 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“lay_summary_pMHC_personalized.docxDocument38 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“lay_summary_CCL26_POSTN.docxDocument38 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“ƒlay_summary_pMHC_nanoparticle.mdText3 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“ƒlay_summary_pMHC_personalized.mdText3 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“ƒlay_summary_CCL26_POSTN.mdText3 KBDevelop a lay summary for the CCL26/POSTN manuscri
πŸ“„Project_Tolera_Pitch_Deck.pdfPDF4.6 MBReview and refine the 3 hackathon manuscripts for
πŸ–Όeoe_burden_infographic.pngFigure210 KBReview and refine the 3 hackathon manuscripts for
πŸ’»build.pyCode7 KBReview and refine the 3 hackathon manuscripts for
πŸ“„EAC_Manuscript.pdfPDF958 KBReview and refine the 3 hackathon manuscripts for
πŸ“„CCL26_POSTN_Manuscript.pdfPDF3.3 MBReview and refine the 3 hackathon manuscripts for
πŸ“„EoE_pMHC_Manuscript_Supplemental.pdfPDF2.8 MBReview and refine the 3 hackathon manuscripts for
πŸ“„EoE_pMHC_Manuscript.pdfPDF2.0 MBReview and refine the 3 hackathon manuscripts for
πŸ“ƒfinal_package_review.mdText6 KBReview and refine the 3 hackathon manuscripts for
πŸ“ƒprize_submission_revised.mdText5 KBReview and refine the 3 hackathon manuscripts for
πŸ“ƒprize_submission_revised.txtText4 KBReview and refine the 3 hackathon manuscripts for
πŸ“ƒdeck_talking_points.mdText5 KBReview and refine the 3 hackathon manuscripts for
πŸ“ŠProject_Tolera_Deck__revised.pptxSlides5.7 MBReview and refine the 3 hackathon manuscripts for
πŸ“ƒwebsite_rebuild_report.mdText5 KBReview and refine the 3 hackathon manuscripts for
πŸ—œproject_tolera_site.zip externalArchive22.5 MBReview and refine the 3 hackathon manuscripts for
πŸ“ƒmanuscript_consistency_report.mdText4 KBReview and refine the 3 hackathon manuscripts for
πŸ“lay_summary_CCL26_POSTN_corrected.docxDocument38 KBReview and refine the 3 hackathon manuscripts for
πŸ“EAC_manuscript_harmonized.docxDocument762 KBReview and refine the 3 hackathon manuscripts for
πŸ“CCL26_manuscript_harmonized.docxDocument2.0 MBReview and refine the 3 hackathon manuscripts for
πŸ“pMHC_manuscript_harmonized.docxDocument458 KBReview and refine the 3 hackathon manuscripts for
πŸ“ƒaccomplishments_ledger.mdText7 KBReview and refine the 3 hackathon manuscripts for
πŸ“ˆaccomplishments_ledger.csvData6 KBReview and refine the 3 hackathon manuscripts for
πŸ“ƒconsistency_decisions.mdText4 KBReview and refine the 3 hackathon manuscripts for
πŸ“ˆplan_finalize-the-project-tolera-hackathon-pa_39ed3738.jsonData8 KBReview and refine the 3 hackathon manuscripts for
πŸ“„EoE_Integrated_Business_Scientific_Report.pdfPDF39 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“Žstyle.cssFile19 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“Žplatform.htmlFile16 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όanydisease_pipeline_dark.pngFigure94 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όanydisease_pipeline_light.pngFigure95 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όtolera_pipeline_dark.pngFigure99 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όtolera_pipeline_light.pngFigure100 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“Žcancer.htmlFile15 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“„Tolera_Reprogramming_Target_Report.pdfPDF1.4 MBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ƒeoe_program_strategy_assessment.mdText16 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆprogram_verdicts.jsonData3 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ƒeoe_reprogramming_target_brief.mdText12 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–ΌprogramB_heatmap.pngFigure219 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–ΌprogramA_heatmap.pngFigure183 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όfig5_druggability.pngFigure187 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆuniprot_localization_top.csvData24 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆtarget_druggability_classification.csvData77 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όfig4_integration.pngFigure332 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆcandidates_annotated.csvData57 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όfig3_programB_amenability.pngFigure424 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆprogramB_consolidated_full.csvData1.5 MBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆprogramB_tolerance_amenability_cotargets.csvData30 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όfig2_programA_dampeners.pngFigure264 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆprogramA_consolidated_full.csvData1.4 MBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆprogramA_th2_dampening_targets.csvData9 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ–Όfig1_readout_coverage.pngFigure247 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“Žde_readout_long.parquet externalFile58.9 MBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆde_qc_summary.csvData214 BExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆreprogramming_panels.csvData2 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆplan_mine-cd4-t-cell-perturb-seq-for-eoe-t-ce_6172abf0.jsonData6 KBExplore the genome-scale CD4+ T cell perturbseq da
πŸ“ˆplan_mine-cd4-t-cell-perturb-seq-for-eoe-th2_6172abf0.jsonData5 KBExplore the genome-scale CD4+ T cell perturbseq da
🎬site_pages.mp4Video1.2 MBCreate a short video that automatically displays e
πŸ“ˆplan_build-a-standalone-browsable-archive-sit_9b44315d.jsonData4 KBCreate a shareable file/archive containing importa
πŸ“„Tolera_Reprogramming_Target_Report (2).pdfPDF1.4 MBUser Uploads
πŸ“ŠTolera_hackathon_video_deck (3) (2).pptxSlides5.7 MBUser Uploads
πŸ“„Tolera_hackathon_video_deck (3) (1).pdfPDF2.1 MBUser Uploads
πŸ”Šaudio1988269321.m4aAudio4.2 MBUser Uploads
πŸ–ΌScreenshot 2026-07-10 at 2.55.13β€―PM.pngFigure562 KBUser Uploads
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