External data files

These 9 files are too large or not suitable for web hosting (single-cell .h5ad objects, large media, and archive bundles totalling several GB). They remain in the project's data store and are reproducible from the public sources noted below. Everything else is bundled directly in this archive — see All artifacts.

epithelial_traj.h5ad 1.04 GB

Epithelial trajectory / pseudotime AnnData object derived from the project's EoE single-cell data during Phase-1 analysis. No source GEO accession was recovered for this derived object from its producing session; regenerable via that session's pipeline.

Produced in session: Develop a comprehensive project plan for Phase 1 that includ

gse218607_slim.h5ad 1.08 GB

Single-cell RNA-seq (slimmed) derived from GEO GSE218607. Download raw data from GEO; regenerate slim object via the Phase-1 pipeline in the producing session.

Source accessions: GSE218607

Produced in session: Develop a comprehensive project plan for Phase 1 that includ

tier1_harmonized_bundle.tar.gz 25.2 MB

Harmonized tier-1 dataset bundle (compressed). Included small bundles are in the archive; this one exceeds the size cap.

Produced in session: Develop a comprehensive project plan for Phase 1 that includ

celiac_sc_slim.h5ad 28.5 MB

Celiac single-cell object harmonized from GEO GSE131705 / GSE146190 / GSE164883.

Source accessions: GSE131705, GSE146190, GSE164883

Produced in session: Adapt and apply our EoE research framework and methodologies

celiac_bulk_harmonized.pkl 22.3 MB

Harmonized celiac bulk transcriptomic object from GEO GSE131705 / GSE146190 / GSE164883.

Source accessions: GSE131705, GSE146190, GSE164883

Produced in session: Adapt and apply our EoE research framework and methodologies

site_walkthrough.mp4 43.1 MB

Screen-recorded walkthrough video of the Project Tolera showcase site (43 MB).

Produced in session: Create a bare bones slide deck walking through the 3-minute

Tolera_hackathon_video_deck.pptx 50.3 MB

Full hackathon video slide deck (50 MB PowerPoint). A smaller PDF/deck version is bundled.

Produced in session: Create a bare bones slide deck walking through the 3-minute

project_tolera_site.zip 22.5 MB

Full source of the existing 'Project Tolera' showcase site (separate deployable).

Produced in session: Review and refine the 3 hackathon manuscripts for consistenc

de_readout_long.parquet 58.9 MB

Long-format differential-expression readout table from the CD4+ T-cell Perturb-seq analysis.

Produced in session: Explore the genome-scale CD4+ T cell perturbseq dataset to i